• Dr. Michael Disher

Genetic modification shows promise for preventing hereditary hearing loss


Pregnant woman smiling down at belly

A mitochondrial defect is responsible for a type of human hereditary deafness that worsens over time and can lead to profound hearing loss. Using a genetically-modified mice model with a mitochondrial dysfunction that results in a similar premature hearing loss, researchers showed that precise genetic reduction of an enzyme, AMP kinase (AMPK), can rescue the hearing loss. Their results are reported in the American Journal of Pathology.



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